Regulation of the Injury-Immune Response in the Central Nervous System: Allostasis and Allostatic Load in Immunity
作者： Karen Bulloch , Bruce S. McEwen
DOI: 10.1016/B978-012532104-4/50016-0
关键词:
摘要: Publisher Summary This chapter reviews the emerging area of research after summarizing key concepts and describing systems that are involved. In order to understand role injury-immune-healing responses (IIHR) trauma in central nervous system (CNS), one must have a clear understanding mechanisms underlying regional regulation IIHR, relationship between adaptive body challenge exacerbation IIHR leads pathophysiology. The is not isolated from immune system. Rather, it should be viewed as tertiary tissue, elements immune-system function CNS play an important well normal adaptation plasticity. neuropeptide CGRP appears particularly potent local-tissue mediator Immune-cell trafficking into brain may mechanism respond damage, even, perhaps, physiological processes.
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