Increased cerebral blood flow after leukapheresis for acute myelogenous leukemia

摘要: Leukapheresis is often considered in the management of acute myelogenous leukemia (AML) with hyperleukocytosis and its sequelae, including myocardial infarction, pulmonary complications, stroke. It utilized on assumption that leukapheresis improves blood rheology. We present a woman AML history meningioma encasing her left internal carotid artery. She presented symptoms ischemia. As white cell continued to rise despite initiation hydroxyurea therapy, she underwent emergently. Transcranial Doppler ultrasound demonstrated increased flow velocities right middle cerebral arteries, which normalized after leukapheresis. This first documentation leukapheresis, combination hydroxyurea, hemodynamics patient AML.