MET Amplification Leads to Gefitinib Resistance in Lung Cancer by Activating ERBB3 Signaling

作者: Jeffrey A Engelman , Kreshnik Zejnullahu , Tetsuya Mitsudomi , Youngchul Song , Courtney Hyland

DOI: 10.1016/S1040-1741(08)79219-4

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摘要: … MET signaling underlies the acquired resistance to gefitinib, we examined whether MET inhibition suppressed growth of the resistant … -665752, a MET tyrosine kinase inhibitor, alone or …

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