LINE-1 and Alu hypomethylation in mucoepidermoid carcinoma
作者： Porntipa Sirivanichsuntorn , Somboon Keelawat , Kittipong Danuthai , Apiwat Mutirangura , Keskanya Subbalekha
关键词:
摘要: Background Mucoepidermoid carcinoma (MEC) can be classified into low-, intermediate-, and high-grade tumors based on its histological features. MEC is mainly composed of three cell types (squamous or epidermoid, mucous intermediate cells), which correlates with the grade reflects clinical behavior. Most cancers exhibit reduced methylation repetitive sequences such as Long INterspersed Element-1 (LINE-1) Alu elements. However, to date very little information available LINE-1 status in MEC. The aim this study was investigate element compare if key differences exist between different types, adjacent normal salivary gland cells, see may reflect grade.
biomedcentral.com
springer.com
core.ac.uk
sci-hub.se 参考文章(53)
Leon Barnes, None, Pathology and Genetics of Head and Neck Tumours ,(2005)
Ronald H. Spiro, Andrew G. Huvos, Richard Berk, Elliot W. Strong, Mucoepidermoid carcinoma of salivary gland origin The American Journal of Surgery. ,vol. 136, pp. 461- 468 ,(1978) , 10.1016/0002-9610(78)90262-3
Yoshihide Okumura, Satoru Miyabe, Takahisa Nakayama, Yukio Fujiyoshi, Hideo Hattori, Kazuo Shimozato, Hiroshi Inagaki, Impact of CRTC1/3-MAML2 fusions on histological classification and prognosis of mucoepidermoid carcinoma. Histopathology. ,vol. 59, pp. 90- 97 ,(2011) , 10.1111/J.1365-2559.2011.03890.X
Göran Stenman, Fusion oncogenes and tumor type specificity: insights from salivary gland tumors Seminars in Cancer Biology. ,vol. 15, pp. 224- 235 ,(2005) , 10.1016/J.SEMCANCER.2005.01.002
Abdelilah Aboussekhra, Role of cancer-associated fibroblasts in breast cancer development and prognosis. The International Journal of Developmental Biology. ,vol. 55, pp. 841- 849 ,(2011) , 10.1387/IJDB.113362AA
Márcio Ajudarte Lopes, Luis Paulo Kowalski, Gilda Cunha Santos, Oslei Paes Almeida, A clinicopathologic study of 196 intraoral minor salivary gland tumours. Journal of Oral Pathology & Medicine. ,vol. 28, pp. 264- 267 ,(2007) , 10.1111/J.1600-0714.1999.TB02036.X
Wolfgang A. Schulz, Jussi P. Elo, Andrea R. Florl, Sari Pennanen, Simon Santourlidis, Rainer Engers, Martin Buchardt, Hans-Helge Seifert, Tapio Visakorpi, Genomewide DNA hypomethylation is associated with alterations on chromosome 8 in prostate carcinoma. Genes, Chromosomes and Cancer. ,vol. 35, pp. 58- 65 ,(2002) , 10.1002/GCC.10092
Tuangtong Pobsook, Keskanya Subbalekha, Phakdee Sannikorn, Apiwat Mutirangura, Improved measurement of LINE-1 sequence methylation for cancer detection. Clinica Chimica Acta. ,vol. 412, pp. 314- 321 ,(2011) , 10.1016/J.CCA.2010.10.030
Mario A. Luna, Salivary mucoepidermoid carcinoma: revisited Advances in Anatomic Pathology. ,vol. 13, pp. 293- 307 ,(2006) , 10.1097/01.PAP.0000213058.74509.D3
Krisanee Chalitchagorn, Shanop Shuangshoti, Nusara Hourpai, Narisorn Kongruttanachok, Pisit Tangkijvanich, Duangporn Thong-ngam, Narin Voravud, Virote Sriuranpong, Apiwat Mutirangura, None, Distinctive pattern of LINE-1 methylation level in normal tissues and the association with carcinogenesis Oncogene. ,vol. 23, pp. 8841- 8846 ,(2004) , 10.1038/SJ.ONC.1208137