Intermediate results of a United States multicenter trial of fenestrated endograft repair for juxtarenal abdominal aortic aneurysms

摘要: Objective This article reports the intermediate-term (24-month) outcomes of a prospective multicenter trial designed to evaluate Zenith Fenestrated AAA Endovascular Graft (Cook Medical, Bloomington, Ind) for treating juxtarenal abdominal aortic aneurysms with short proximal necks. The study goals were safety and preliminary effectiveness device refine patient selection criteria. Methods Five centers in United States enrolled 30 patients ≥50-mm diameter Devices custom-designed each based on measurements from reconstructed computed tomography (CT) data. Follow-up studies included physical examinations, laboratory studies, CT imaging, mesenteric-renal duplex ultrasound flat plate radiographs at hospital discharge, 1, 6, 12 months, yearly thereafter up 5 years. Results During 1-year period, (80% men; mean age, 75 years) aneurysm size 61.4 mm enrolled. In these patients, 77 visceral vessels accommodated by fenestrations located within sealing segment grafts. most common design two renal arteries superior mesenteric artery (66.7%). All prostheses implanted successfully. No lost. Of treated, 27 available 12-month follow-up 23 24-month follow-up. aneurysm-related deaths, ruptures, or conversions observed through 24 months type I III endoleaks observed. Type II noted six (26.1%) four (20.0%) months. had growth >5 mm. Aneurysm decreased 16 (69.6%) was stable remaining Eight experienced event (4 stenoses, 2 occlusions, infarcts). underwent secondary interventions. failure developed requiring dialysis. Conclusions results this are concordant previous single-center support concept that placement fenestrated endovascular grafts is safe effective experience repair renal/mesenteric stent placement.