Systems, methods, and devices for ultrasonic assessment of cancer and response to therapy

摘要: Microbubbles can be injected into the bloodstream of a patient, for example, cancer patient undergoing treatment specifically targeting biological process in tumor. The microbubbles act as vascular contrast agents, which detected vivo using high-frequency ultrasound imaging. have surface chemistry that allows them to bind molecular targets tumor vasculature. After injection, selectively adhere endothelia expressing target receptor. selective adhesion used quantify vasculature vivo. By imaging adhered with ultrasound, an indication how is affected by specific obtained. Such techniques clinical setting rapid determination anti-cancer efficacy individual patients.