Immunogenicity and safety of the human papillomavirus vaccine in patients with autoimmune diseases: A systematic review

作者: Paolo Pellegrino , Sonia Radice , Emilio Clementi

DOI: 10.1016/J.VACCINE.2015.05.041

关键词:

摘要: Whereas safety and efficacy of HPV vaccines in healthy women have been shown several randomised controlled clinical trials post marketing analyses, only few data exist patients affected by autoimmune diseases. These issues are significant as conditions recognised a risk factor for the persistence infection. Herein we review systematise existing literature to assess immunogenicity vaccination with diseases, including systemic lupus erythematosus juvenile idiopathic arthritis. The results our revision suggest that efficacious safe most Yet, some points concern remain be tackled, effects concomitant therapies, disease exacerbation cost-effectiveness such immunisation programmes these populations.

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