摘要: Hyperbaric oxygen therapy (HBOT), the administration of pressurized 100% oxygen, is used as an adjunct to aid healing in selected chronic wounds. Though has had a controversial history, research now elucidating mechanisms by which HBOT helps heal increases growth factors and local wound signaling, while also promoting central stem cell release endothelial progenitor cells from bone marrow via nitric oxide pathways. The clinical data continue accumulate support help hasten healing, reduce amputation rate diabetic ulcers. In appropriate patients, effective, noninvasive, modality that can be healing.