Anti-egfr antibody therapy based on an increased copy number of the egfr gene in tumor tissues

摘要: The invention relates to an individualized and personalized diagnosis therapy of cancer based on specific molecular alterations which occur in tumor tissue patient populations. diagnostic is the findings that proliferation growth EGFR bearing expressing amplified gene copy number may be abolished by anti-EGFR antibodies, while other individual such as mutations occurring tissues are unaffected same antibody treatment.