Rationale-based design of a targeted therapy for cancer

作者: Lee Jason J , Lee Allen J , Lu David M , Lee Ruey-Min

DOI:

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摘要: The methods, compositions, and kits of the invention are related to discovery that lestaurtinib reduces levels pathway activity an SPOP substrate. Accordingly, described herein methods compositions for use in downregulating one or more substrates signaling activities thereof a subject need thereof.

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