Physical studies of myelin I. Thermal analysis

摘要: Abstract 1. Myelin isolated from ox brain white matter and the lipids extracted this material have been examined by thermal analysis techniques including differential scanning calorimetry. The results provide information about organisation of water in myelin structure. 2. On drying a crystallisation precipitation lipid cholesterol takes place. Endothermic transitions associated with can then be observed. 3. total extract does not show detectable endothermic transition but cholesterol-free does. In absence cholesterol, part is crystalline at body temperature. 4. With wet no are detectable. case appear to organised into single phase. presence membrane prevent crystallising. 5. To maintain there appears critical amount required. This unfreezable 0° may correspond “bound” water.