The impact of short stature on health-related quality of life in children with chronic kidney disease.
作者： Amira Al-Uzri , Matthew Matheson , Debbie S Gipson , Susan R Mendley , Stephen R Hooper
DOI: 10.1016/J.JPEDS.2013.03.016
关键词:
摘要: Objectives To compare the health-related quality of life (HRQoL) children with chronic kidney disease (CKD) and short stature (SS) that CKD normal height (NH), to evaluate impact catch-up growth hormone (GH) use on HRQoL, describe concordance perceptions HRQoL between SS NH their parents. Study design Four hundred eighty-three and/or parents enrolled in multicenter Chronic Kidney Disease Children study who had completed Pediatric Quality Life Inventory (Version 4.0) at least 2 Chronic visits composed this substudy population. Participants were dichotomized into or groups. The demographic characteristics varied baseline (sex, glomerular filtration rate, parent education) controlled for main analysis evaluating GH HRQoL. Results Multivariate modeling (controlling confounding variables) revealed a significant association both parent–proxy reports child physical functioning ( P Conclusion finding gains are associated increases social by report provides additional support interventions improve CKD. importance is supported our results.
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