Withdrawal from acute morphine dependence is accompanied by increased anxiety-like behavior in the elevated plus maze

作者: Zhongqi Zhang , Gery Schulteis

DOI: 10.1016/J.PBB.2008.01.013

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摘要: Pretreatment with a single moderate dose of morphine (eg 5.6-10 mg/kg) 4-24 hr prior to challenge with an opioid antagonist such as naloxone results in reliable expression of …

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