Highly undersampled contrast-enhanced MRA with iterative reconstruction: Integration in a clinical setting.

摘要: Purpose To integrate, optimize, and evaluate a three-dimensional (3D) contrast-enhanced sparse MRA technique with iterative reconstruction on standard clinical MR system. Methods Data were acquired using highly undersampled Cartesian spiral phyllotaxis sampling pattern reconstructed directly the system an SENSE technique. Undersampling, regularization, number of iterations optimized validated based phantom experiments patient data. Sparse whole head (field view: 265 × 232 179 mm3) was investigated in 10 examinations. Results High-quality images 30-fold undersampling, resulting 0.7 mm isotropic resolution within s acquisition, obtained. After optimization regularization factor reconstruction, it possible to reconstruct excellent quality six minutes per 3D volume. Initial results (CEMRA) patients demonstrated high-quality whole-head first-pass for both arterial venous contrast phases. Conclusion While MRI techniques have not yet reached routine, this study demonstrates technical feasibility CEMRA setting. has potential become viable alternative where conventional is too slow or does provide sufficient spatial resolution. Magn Reson Med, 2014. © 2014 Wiley Periodicals, Inc.