Nonconvulsive electrographic seizures after traumatic brain injury result in a delayed, prolonged increase in intracranial pressure and metabolic crisis.

作者: Paul M. Vespa , Chad Miller , David McArthur , Mathew Eliseo , Maria Etchepare

DOI: 10.1097/01.CCM.0000295667.66853.BC

关键词:

摘要: Objective:To determine whether nonconvulsive electrographic post-traumatic seizures result in increases intracranial pressure and microdialysis lactate/pyruvate ratio.Design:Prospective monitoring with retrospective data analysis.Setting:Single center academic neurologic intensive care unit.Patie

参考文章(20)
Per Enblad, Johann Valtysson, Jesper Andersson, Anders Lilja, Sven Valind, Gunnar Antoni, Bengt Långström, Lars Hillered, Lennart Persson, Simultaneous Intracerebral Microdialysis and Positron Emission Tomography in the Detection of Ischemia in Patients with Subarachnoid Hemorrhage Journal of Cerebral Blood Flow and Metabolism. ,vol. 16, pp. 637- 644 ,(1996) , 10.1097/00004647-199607000-00014
Rachel C. Hoover, Melissa Motta, Jason Davis, Kathryn E. Saatman, Scott T. Fujimoto, Hilaire J. Thompson, John F. Stover, Marc A. Dichter, Roy Twyman, H. Steve White, Tracy K. McIntosh, Differential Effects of the Anticonvulsant Topiramate on Neurobehavioral and Histological Outcomes following Traumatic Brain Injury in Rats Journal of Neurotrauma. ,vol. 21, pp. 501- 512 ,(2004) , 10.1089/089771504774129847
Elisa Roncati Zanier, Stefan M. Lee, Paul M. Vespa, Christopher C. Giza, David A. Hovda, Increased hippocampal CA3 vulnerability to low-level kainic acid following lateral fluid percussion injury. Journal of Neurotrauma. ,vol. 20, pp. 409- 420 ,(2003) , 10.1089/089771503765355496
W. B. Jennett, W. Lewin, Traumatic epilepsy after closed head injuries. Journal of Neurology, Neurosurgery, and Psychiatry. ,vol. 23, pp. 295- 301 ,(1960) , 10.1136/JNNP.23.4.295
A. J. Williams, F. C. Tortella, X. M. Lu, J. E. Moreton, J. A. Hartings, Antiepileptic Drug Treatment of Nonconvulsive Seizures Induced by Experimental Focal Brain Ischemia Journal of Pharmacology and Experimental Therapeutics. ,vol. 311, pp. 220- 227 ,(2004) , 10.1124/JPET.104.069146
Marvin Bergsneider, David A. Hovda, Ehud Shalmon, Daniel F. Kelly, Paul M. Vespa, Neil A. Martin, Michael E. Phelps, David L. McArthur, Michael J. Caron, Jess F. Kraus, Donald P. Becker, Cerebral hyperglycolysis following severe traumatic brain injury in humans: a positron emission tomography study Journal of Neurosurgery. ,vol. 86, pp. 241- 251 ,(1997) , 10.3171/JNS.1997.86.2.0241
Paul M. Vespa, David McArthur, Kristine O'Phelan, Thomas Glenn, Maria Etchepare, Daniel Kelly, Marvin Bergsneider, Neil A. Martin, David A. Hovda, Persistently low extracellular glucose correlates with poor outcome 6 months after human traumatic brain injury despite a lack of increased lactate: a microdialysis study. Journal of Cerebral Blood Flow and Metabolism. ,vol. 23, pp. 865- 877 ,(2003) , 10.1097/01.WCB.0000076701.45782.EF
Mark Parkin, Sarah Hopwood, Deborah A Jones, Parastoo Hashemi, Hans Landolt, Martin Fabricius, Martin Lauritzen, Martyn G Boutelle, Anthony J Strong, Dynamic changes in brain glucose and lactate in pericontusional areas of the human cerebral cortex, monitored with rapid sampling on-line microdialysis: relationship with depolarisation-like events. Journal of Cerebral Blood Flow and Metabolism. ,vol. 25, pp. 402- 413 ,(2005) , 10.1038/SJ.JCBFM.9600051