Contribution of Clostridium perfringens type A with beta2 toxin gene in aetiology of porcine enteric diseases. A case report

作者: B Wasinski

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摘要: The aim of the report was to describe three cases fatal enteritis in piglets, from which Clostridium perfringens type A strains carrying β2 toxin gene were isolated as only specific pathogen. Six animals submitted for study, originated farms. age piglets ranged two days weeks. Animals each farm showed at necropsy different intensity pathological changes. typing performed by use PCR method. All presented expression α ELISA.

参考文章(9)
Helena Raškova, Jiři Vaněček, PHARMACOLOGY OF BACTERIAL TOXINS Pharmacological Reviews. ,vol. 16, pp. 1- 45 ,(1964)
R W Titball, S E Hunter, K L Martin, B C Morris, A D Shuttleworth, T Rubidge, D W Anderson, D C Kelly, Molecular cloning and nucleotide sequence of the alpha-toxin (phospholipase C) of Clostridium perfringens. Infection and Immunity. ,vol. 57, pp. 367- 376 ,(1989) , 10.1128/IAI.57.2.367-376.1989
Henricus L.B.M. Klaasen, Marc J.C.H. Molkenboer, Jelle Bakker, Raymond Miserez, Hansjürg Häni, Joachim Frey, Michel R. Popoff, Johannes F. Bosch, Detection of the β2 toxin gene of Clostridium perfringens in diarrhoeic piglets in The Netherlands and Switzerland Fems Immunology and Medical Microbiology. ,vol. 24, pp. 325- 332 ,(1999) , 10.1111/J.1574-695X.1999.TB01301.X
M. Waters, A. Savoie, H. S. Garmory, D. Bueschel, M. R. Popoff, J. G. Songer, R. W. Titball, B. A. McClane, M. R. Sarker, Genotyping and Phenotyping of Beta2-Toxigenic Clostridium perfringens Fecal Isolates Associated with Gastrointestinal Diseases in Piglets Journal of Clinical Microbiology. ,vol. 41, pp. 3584- 3591 ,(2003) , 10.1128/JCM.41.8.3584-3591.2003
Maryse Gibert, Colette Jolivet-Renaud, Michel R. Popoff, Beta2 toxin, a novel toxin produced by Clostridium perfringens. Gene. ,vol. 203, pp. 65- 73 ,(1997) , 10.1016/S0378-1119(97)00493-9
Dawn M. Bueschel, B. Helen Jost, Stephen J. Billington, Hien T. Trinh, J. Glenn Songer, Prevalence of cpb2, encoding beta2 toxin, in Clostridium perfringens field isolates: correlation of genotype with phenotype Veterinary Microbiology. ,vol. 94, pp. 121- 129 ,(2003) , 10.1016/S0378-1135(03)00081-6
J R Czeczulin, P C Hanna, B A McClane, Cloning, nucleotide sequencing, and expression of the Clostridium perfringens enterotoxin gene in Escherichia coli Infection and Immunity. ,vol. 61, pp. 3429- 3439 ,(1993) , 10.1128/IAI.61.8.3429-3439.1993
J. Sakurai, Toxins of Clostridium perfringens. Reviews in Medical Microbiology. ,vol. 6, pp. 175- 185 ,(1995)