Ancestry of alleles and extinction of genes in populations with defined pedigrees
作者： E. A. Thompson
关键词:
摘要: The paper presents, without mathematical formalities, two computational approaches to the analysis of pedigrees. One provides a method for inferring ancestry rare alleles observed in population. other probabilities that specified combinations founder genes survive this current emphasis both is upon importance joint probabilities. If some survive, others have smaller probability doing so also. an allele descends from given individual, it likely appear also individuals sharing same lines descent.
sci-hub.se 参考文章(11)
Kidd, Kidd Kk, Wolf B, Hsia E, Genetics of propionic acidemia in a Mennonite-Amish kindred. American Journal of Human Genetics. ,vol. 32, pp. 236- 245 ,(1980)
Gene Extinction and Allelic Origins in Complex Genealogies Proceedings of The Royal Society B: Biological Sciences. ,vol. 219, pp. 241- 251 ,(1983) , 10.1098/RSPB.1983.0072
Sewall Wright, Coefficients of Inbreeding and Relationship The American Naturalist. ,vol. 56, pp. 330- 338 ,(1922) , 10.1086/279872
D. F. Roberts, The demography of Tristan da Cunha. Population Studies-a Journal of Demography. ,vol. 25, pp. 465- 479 ,(1971) , 10.1080/00324728.1971.10405818
S.K. Buehler, G. Fodor, W.H. Marshall, F. Firme, G.R. Fraser, P. Vaze, COMMON VARIABLE IMMUNODEFICIENCY, HODGKIN'S DISEASE, AND OTHER MALIGNANCIES IN A NEWFOUNDLAND FAMILY The Lancet. ,vol. 305, pp. 195- 197 ,(1975) , 10.1016/S0140-6736(75)91361-6
E. A. THOMPSON, A recursive algorithm for inferring gene origins Annals of Human Genetics. ,vol. 47, pp. 143- 152 ,(1983) , 10.1111/J.1469-1809.1983.TB00981.X
E. A. THOMPSON, Ancestral inference. II. The founders of Tristan da Cunha. Annals of Human Genetics. ,vol. 42, pp. 239- 253 ,(1978) , 10.1111/J.1469-1809.1978.TB00656.X
C. Cannings, E. A. Thompson, M. H. Skolnick, Probability functions on complex pedigrees Advances in Applied Probability. ,vol. 10, pp. 26- 61 ,(1978) , 10.2307/1426718
E. A. THOMPSON, Pedigree analysis of Hodgkin's disease in a Newfoundland genealogy. Annals of Human Genetics. ,vol. 45, pp. 279- 292 ,(1981) , 10.1111/J.1469-1809.1981.TB00339.X
G. KARIGL, A recursive algorithm for the calculation of identity coefficients. Annals of Human Genetics. ,vol. 45, pp. 299- 305 ,(1981) , 10.1111/J.1469-1809.1981.TB00341.X