The impact of pre-hospital thrombolytic treatment on re-infarction rates : analysis of the Myocardial Infarction National Audit Project (MINAP)
作者： S Horne , C Weston , T Quinn , A Hicks , L Walker
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摘要: Objective: To examine the frequency and determinants of re-infarction after thrombolytic treatment ST-elevation myocardial infarction (STEMI). Design: Observational study national registry. Setting: Emergency ambulance services admitting hospitals in England Wales. Patients: 35 356 patients with STEMI given 2005–6. Main outcome measures: Re-infarction during hospital admission. Results: For 22 391 (63.3%) presence or absence was recorded, 1460 (6.5%) had re-infarction. rates in-hospital were similar for reteplase tenecteplase (6.4%). When interval from pre-hospital to arrival greater than 30 minutes 12.5% reteplase, 11.4% tenecteplase. Overall, higher (9.6% vs 6.6%, p = 0.005). After multivariate analysis independent predictors treatment, OR 1.44 (95% CI 1.21 1.71, p Conclusion: Pre-hospital associated rates. Longer intervals high both reteplase. Differences use adjunctive anti-thrombotic therapy two environments may underlie differences bleeding complications observed between treatment.
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coventry.ac.uk
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