Role of thrombolysis in reperfusion therapy for management of AMI: Indian scenario

摘要: Cardiovascular disorders are the major cause of morbidity & mortality globally as well in India. In 2008, out 57 million deaths globally; around 63% (i.e., nearly 30 deaths) were due to non-communicable diseases.1 diseases accounts for half worldwide, thus becoming leading death diseases. Approximately, 80% these have been reported occur low and middle-income countries.1 Moreover, nine premature (viz. age < 60 years); eight occurred countries. With 6.8% 5.0% disability-adjusted life-years (DALYs) lost, CAD is second largest causes disease burden population aged 15 years older globally.1 1.1. Trends cardiovascular India Cardiovascular assumed epidemic proportions India well. The Global Burden Diseases (GBD) study estimated from coronary heart (CHD) be 1.6 year 2000 which increase ∼64 by 2015.2 projected rise CVD expected make it prime contributor total morbidity.2 Reports on Indians shown that Asian at 3–4 times higher risk than white Americans, 6 Chinese, 20 Japanese.3 Various independent epidemiological studies conducted North suggest prevalence has increased 1% 1960 10.5% 1998 urban population.3 A CAD, ranging 11.0% 14.2%, South India.3 Taking into account size Indian population, rates indicate a large number can attributed CAD.3