Progress in Biomedical Applications of Functionalized Nucleic Acid Nanodevices (NANDs)
作者： Guangqi Wu , Hua Lu
关键词:
摘要: DNA and RNA are building blocks with excellent programmability for nanoscale assembly. Owing to their appealing properties such as precision in bottom-up fabrication, enhanced stability cellular internalization, designed nucleic acid nanodevices (NANDs) have been widely explored biomedical research. Compared pristine acids, chemically modified NANDs exhibit a wider spectrum of applicability. In this Focus Review, we highlight recent advances functionalized small molecules, peptides/proteins or inorganic materials, elucidate promising future application.
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