Use of focused beam reflectance measurement (FBRM) and process video imaging (PVI) in a modified mixed suspension mixed product removal (MSMPR) cooling crystallizer

摘要: Abstract The FBRM instrument is a ‘powerful’ tool developed by Lasentec as an ‘in situ’ particle monitoring technique for in-line real-time measurement of size. This was successfully used to monitor steady-state operation in modified MSMPR crystallizer. also estimate crystallization kinetics. size measurements were complimented process video imaging (PVI) system ‘ in-house ’ (Microscopy and Microanalysis, 6 (Suppl. 2) (2000) 996–997), visualize habit crystal behaviour within A comparison the distributions measured low angle light scattering (LALLS) made, showing poor sensitivity particles less than 1 μm hence not suitable kinetics this organic system.