Purification of Trypanosoma cruzi surface proteins involved in adhesion to host cells.

作者: Fernando Villalta , Maria F. Lima , Lin Zhou

DOI: 10.1016/0006-291X(90)90764-E

关键词:

摘要: We have identified four surface 83 kDa proteins of pI values 6.3, 6.4, 6.5 and 6.6 in T. cruzi trypomastigotes which specifically bind to rat heart myoblasts. These were purified by isoelectric focusing anion-exchange chromatography an FPLC system. inhibit the attachment myoblasts a concentration-dependent manner, indicating that these trypomastigote mediate

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