Clinicopathological and prognostic features of primary clear cell carcinoma of the liver
作者： Zhisheng Liu , Weidong Ma , Huikai Li , Qiang Li
DOI: 10.1111/J.1872-034X.2007.00264.X
关键词:
摘要: Aim: Primary clear cell carcinoma of the liver (PCCCL) is a subgroup primary hepatocellular (HCC), pathologically characterized by diffuse cells tumor, showing cytoplasm that does not stain with hematoxylin–eosin. At present, its clinicopathological and prognostic features are fully clarified. This study aims to clarify PCCCL. Methods: The data 43 patients PCCCL treated hepatectomy in our hospital from January 1999 December 2003 were retrospectively analyzed. Results: χ2-test showed positive rate hepatitis C virus (HCV) infection capsule formation group, which was markedly higher than common type HCC (CHCC) group (P = 0.000 P = 0.005). Meanwhile, vascular invasion notably lower but there no significant differences between twogroups 0.129). Kaplan–Meier method 1-, 3-, 5-year survival rates significantly CHCC 0.021). prognosis related formation, invasion, cirrhosis, ratio. ratio 0.011). Conclusion: notable included HCV infection, invasion. better cells.
sci-hub.se 参考文章(43)
Henning E. Adamek, Andreas Spiethoff, Volker Kaufmann, Ralf Jakobs, Juergen F. Riemann, Primary clear cell carcinoma of noncirrhotic liver: immunohistochemical discrimination of hepatocellular and cholangiocellular origin. Digestive Diseases and Sciences. ,vol. 43, pp. 33- 38 ,(1998) , 10.1023/A:1018859617522
Shinichi Kiso, Iwao Yabuuchi, Shinji Tamura, Kenji Takaishi, Yasuo Matsuda, Seiichiro Tarui, Yasuhiro Shirai, Minoru Nishioka, Nobuyuki Ito, Sumio Kawata, Elevated Levels of Transforming Growth Factor β Messenger RNA and Its Polypeptide in Human Hepatocellular Carcinoma Cancer Research. ,vol. 51, pp. 4080- 4083 ,(1991)
Li Qiang, Li Huikai, Kelly Butt, P Peter Wang, Xishan Hao, None, Factors Associated with Disease Survival after Surgical Resection in Chinese Patients with Hepatocellular Carcinoma World Journal of Surgery. ,vol. 30, pp. 439- 445 ,(2006) , 10.1007/S00268-005-0608-6
C. L. Lai, P. C. Wu, K. C. Lam, D. Todd, Histologic prognostic indicators in hepatocellular carcinoma Cancer. ,vol. 44, pp. 1677- 1683 ,(1979) , 10.1002/1097-0142(197911)44:5<1677::AID-CNCR2820440522>3.0.CO;2-D
Lukumuena O. Kashala, Mbowa M. R. Kalengayi, Béatrice Conne, Yusuf Kapanci, Philippe C. Frei, Paul H. Lambert, Histopathologic features of hepatocellular carcinoma in Zaire Cancer. ,vol. 65, pp. 130- 134 ,(1990) , 10.1002/1097-0142(19900101)65:1<130::AID-CNCR2820650126>3.0.CO;2-S
Yoshizumi Shintani, Hajime Fujie, Hideyuki Miyoshi, Takeya Tsutsumi, Kazuhisa Tsukamoto, Satoshi Kimura, Kyoji Moriya, Kazuhiko Koike, Hepatitis C virus infection and diabetes: direct involvement of the virus in the development of insulin resistance Gastroenterology. ,vol. 126, pp. 840- 848 ,(2004) , 10.1053/J.GASTRO.2003.11.056
A. M. Oliveira, L. A. Erickson, L. J. Burgart, R. V. Lloyd, Differentiation of primary and metastatic clear cell tumors in the liver by in situ hybridization for albumin messenger RNA. The American Journal of Surgical Pathology. ,vol. 24, pp. 177- 182 ,(2000) , 10.1097/00000478-200002000-00002
Michael R. Charlton, Paul J. Pockros, Stephen A. Harrison, Impact of obesity on treatment of chronic hepatitis C Hepatology. ,vol. 43, pp. 1177- 1186 ,(2006) , 10.1002/HEP.21239
Konstantinos C. Thomopoulos, Vassiliki Arvaniti, Athanasios C. Tsamantas, Dimitra Dimitropoulou, Charalambos A. Gogos, Dimitrios Siagris, George J. Theocharis, Chryssoula Labropoulou-Karatza, Prevalence of liver steatosis in patients with chronic hepatitis B: a study of associated factors and of relationship with fibrosis. European Journal of Gastroenterology & Hepatology. ,vol. 18, pp. 233- 237 ,(2006) , 10.1097/00042737-200603000-00002
D. M. Parkin, F. Bray, J. Ferlay, P. Pisani, Global cancer statistics, 2002. CA: A Cancer Journal for Clinicians. ,vol. 55, pp. 74- 108 ,(2005) , 10.3322/CANJCLIN.55.2.74