作者: J Stabel
DOI: 10.1016/S0378-1135(00)00331-X
关键词:
摘要: The host immune response to infection with Mycobacterium paratuberculosis is paradoxical, strong cell-mediated responses during the early, subclinical stages of and humoral late clinical disease. Cell-mediated modulated by various T cell subsets are essential provide protective immunity prevent progression Secretion cytokines populations serves activate macrophages kill ingested M. as well other contain infection. This paper reviews current knowledge in based upon studies research using mouse models.