Off-pump CABG Attenuates Myocardial Enzyme Leakage but Not Postoperative Brain Natriuretic Peptide Secretion

摘要: BACKGROUND Off-pump coronary artery bypass surgery is considered to be less invasive compared with a conventional surgery, while objective assessment of its invasiveness has not been well established. The grade off-pump CABG was evaluated by biochemical markers released from the myocardium. METHODS Perioperative serial changes myocardial enzyme leakage (creatine kinase-MB isoenzyme and troponin T) were in 217 patients who underwent (28 189 patients). Serial atrial natriuretic peptide brain secretion as heart failure also 12 49 patients. RESULTS Myocardial significantly group, increase peptides similar both groups peak at first postoperative day (246+/-46 pg/ml group 312+/-57 pg/dl group). CONCLUSIONS Although seems cells aspect leakage, ischemic stress assessed that CABG. Careful monitoring management throughout period mandatory even procedure.