Knock-out mouse models used to study neurobiological systems.

摘要: The use of knock-out mice to examine problems relevant neurobiology is rapidly expanding. Knock-out have been used study the role particular gene products in biochemical processes, mediating effects neuropharmacological substances, and complex behaviors. advantages disadvantages using neurobiological are discussed here, current state technology reviewed briefly. elucidate functions molecules involved signaling through various neurotransmitter systems then examined. Approaches such as basis learning memory molecular drug abuse also explored.