Psychosocial burden and glycemic control during the first 6 years of diabetes: results from the SEARCH for Diabetes in Youth study.

摘要: Abstract Purpose To evaluate the psychosocial burden of adolescents with diabetes, determine trajectory burden, and examine interdependent relationships between glycemic control across first 6 years diabetes. Methods Data from SEARCH for Diabetes in Youth, an observational study U.S. children diagnosed diabetes before age 20, were collected during visits conducted at baseline then 12, 24, 60 months after baseline. Blood was drawn, clinical demographic information collected, evaluated using standardized depression generic diabetes-specific health-related quality life (QOL) surveys. Results Among 1,307 (mean age, 14.1±2.5 years) data, 1,026 had type 1 281 2 For those a 60-month follow-up visit, glycated hemoglobin (A 1c ) values rose 1.5% (type 1, 7.7%–9.3% 2, 7.3%–8.8%). Adolescents reported more poorer QOL than each type, there similar risk factors higher A values: longer duration, ethnic minority status, declining ( p increasing QOL, unexpected finding. Younger end study. Conclusions Significant deterioration marks adolescents. Psychosocial particularly poor is contributor to suboptimal outcomes.