Development of the human fetal cerebellum in the second trimester: a post mortem magnetic resonance imaging evaluation.

作者: Fei Liu , Zhonghe Zhang , Xiangtao Lin , Gaojun Teng , Haiwei Meng

DOI: 10.1111/J.1469-7580.2011.01418.X

关键词:

摘要: The cerebellum is one of the most important structures in posterior cranial fossa, but characterization its development by magnetic resonance imaging (MRI) incomplete. We scanned 40 fetuses that had no morphological brain disorder at 14-22 weeks gestation using 7.0 T MRI. Amira 4.1 software was used to determine parameters fetal cerebellum, which included cerebellar volume (CV), transverse diameter (TCD), and length width vermis. relationship between these measurements gestational age (GA) analysed. found primary fissure visible week 14 gestation. From 16, prepyramidal fissure, secondary dentate nucleus could be identified. posterolateral fourth ventricle were recognized 17, whereas tentorium 20. relationships GA CV, TCD, vermis described adequately second-order polynomial regression curves. ratios TCD decreased with GA. These results show MRI can trajectory clearly. They increase our understanding normal fetus, will facilitate diagnosis pathological intrauterine changes cerebellum.

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