An analysis of the OPTN/UNOS Liver Transplant Registry.

摘要: Based on data reported to the OPTN/UNOS Liver Transplant Registry between 1988-2004: 1. There was a very small difference in 5-year graft survival rates comparing living and deceased donors adult (4.3%) pediatric patients (2.4%). 2. Although of split liver transplants were lower than whole grafts before 1998, results more recent (65.8%) have become comparable those (66.5%). Among recipients good condition, (67.7%) (70.0%) yielded equivalent rates. 3. Lower noted ABO incompatible grafts, non-heartbeating donors, regrafted patients, who ICU transplantation. 4. no recipient gender effect transplant outcome. 5. Primary disease distributions different for races. largest fraction white had alcoholic cirrhosis. Asians, Type B cirrhosis most frequent. biliary atresia constituted majority patients. Most with alpha-1 antitrypsin deficiency white. Autoimmune hepatitis frequently found among black 6. (60.2%) whites (68.1%), Hispanics (67.6%), Asians (68.0%), PBC (73.3%) PSC (69.9%) similar (78.1%) (73.6%) (75.3%) (77.1%). 7. Zero HLA-A,-B,-DR mismatched livers rapid early failures. HLA matching correlated autoimmune but not 8. Short-term has improved steadily since 1990. However, long-term after first year actually declined over time. 9. In transplants, autoimmune-related diseases, (77.3%), (73.3%), AIH (74.2%) higher (71.5%) C (63.2%). 10. (75.4%), (70.8%), alpha-1-antitrypsin (85.0%) high rates, except acute failure (61.6%). 11. Hepatitis recurrence is now one major causes adults. Thrombosis factor transplants.