Effects of pre- and postnatal nutrition interventions on child growth and body composition: the MINIMat trial in rural Bangladesh.

摘要: Background : Nutritional insults and conditions during fetal life infancy influence subsequent growth body composition of children. Objectives Effects maternal food micronutrient supplementation exclusive breastfeeding counseling on offspring aged 0–54 months their at 54 age were studied. Methods In the MINIMat trial (ISRCTN16581394) in Matlab, Bangladesh, pregnant women randomized to early (around 9 weeks) or usual invitation 20 one three daily supplements: 30-mg Fe 400-µg folic acid (Fe30F), 60-mg (Fe60F), multiple supplements (MMS). The also (EBF) health messages. Results No differences background characteristics observed among intervention groups. There was no differential effect prenatal interventions birthweight birthlength. Early reduced level stunting from up boys (average difference – 6.5% units, 95% confidence interval [CI] 1.7–11.3,  p =0.01) but not girls 2.4% CI −2.2–7.0, =0.31). MMS resulted more compared standard Fe60F 4.8% 0.8–8.9,  =0.02). Breastfeeding prolonged duration EBF (difference 35 days, 30.6–39.5,  <0.001). Neither pregnancy nor influenced children age. Conclusion occurrence months, while increased proportion stunting. Food did affect effects postnatal suggest programming life. Keywords : body composition; child growth; supplementation; micronutrients; (Published: 13 December 2013) This article has been commented by Elisabet Forsum. Read her commentary here . Citation Glob Health Action 2013,  6 22476 - http://dx.doi.org/10.3402/gha.v6i0.22476