Methods and Platforms for the Quantification of Splice Variants' Expression

作者: Laurent Bracco , Emeline Throo , Olivier Cochet , Richard Einstein , Florence Maurier

DOI: 10.1007/978-3-540-34449-0_1

关键词:

摘要: The relatively limited number of human protein encoding genes highlights the importance diversity generated at level mRNA transcripts. As alternative RNA splicing plays a key role in mediating this diversity, it becomes critical to develop tools and platforms that will deliver quantitative information on specific expression levels associated with splice isoforms. This chapter describes constraints by global transcriptome analysis state-of-the-art techniques products available scientific community.

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