Overview of influenza viruses.

摘要: The influenza virus (IV) is still of great importance as it poses an immanent threat to humans and animals. Among the three IV-types (A, B, C) A viruses are clinically most important being responsible for severe epidemics in domestic Aerosol droplets transmit that causes a respiratory disease can lead pneumonia ultimately death. high mutation rate combined with replication allows rapidly adapt changes environment. Thereby, IV escape existing immunity become resistant drugs targeting virus. This annual demands new compositions yearly vaccines. Furthermore, due nature their segmented genome, recombine segments. eventually generation ability replicate novel antigenic properties be cause pandemic outbreak. For its propagation binds target cells enters cell genome. Newly produced viral proteins genomes packaged at membrane where progeny virions released. As all depends on cellular functions factors own propagation, therefore intensively interact cells. dependency opens possibilities anti-viral strategies.