Theoretical and experimental investigation of drug-polymer interaction and miscibility and its impact on drug supersaturation in aqueous medium.
作者： Shrawan Baghel , Helen Cathcart , Niall J. O’Reilly
DOI: 10.1016/J.EJPB.2016.06.024
关键词:
摘要: … Fourier-transform Infrared (FTIR) Spectroscopy was performed using a Varian 660-IR FT-IR Spectrometer (32 scans at 4 cm −1 resolution). Test samples were mixed with KBr and then …
sci-hub.se 参考文章(53)
Takahiro Matsumoto, George Zografi, Physical properties of solid molecular dispersions of indomethacin with poly(vinylpyrrolidone) and poly(vinylpyrrolidone-co-vinyl-acetate) in relation to indomethacin crystallization. Pharmaceutical Research. ,vol. 16, pp. 1722- 1728 ,(1999) , 10.1023/A:1018906132279
Stephen Z. D. Cheng, Phase Transitions in Polymers: The Role of Metastable States ,(2008)
Sheri L. Shamblin, George Zografi, The effects of absorbed water on the properties of amorphous mixtures containing sucrose. Pharmaceutical Research. ,vol. 16, pp. 1119- 1124 ,(1999) , 10.1023/A:1018960405504
Krishna Bansal, Uttam Singh Baghel, Seema Thakral, Construction and Validation of Binary Phase Diagram for Amorphous Solid Dispersion Using Flory–Huggins Theory Aaps Pharmscitech. ,vol. 17, pp. 318- 327 ,(2016) , 10.1208/S12249-015-0343-8
Jia Liu, Feng Cao, Can Zhang, Qineng Ping, Use of polymer combinations in the preparation of solid dispersions of a thermally unstable drug by hot-melt extrusion Acta Pharmaceutica Sinica B. ,vol. 3, pp. 263- 272 ,(2013) , 10.1016/J.APSB.2013.06.007
Chandan Bhugra, Michael J. Pikal, Role of Thermodynamic, Molecular, and Kinetic Factors in Crystallization from the Amorphous State Journal of Pharmaceutical Sciences. ,vol. 97, pp. 1329- 1349 ,(2008) , 10.1002/JPS.21138
Yiwei Tian, Jonathan Booth, Elizabeth Meehan, David S. Jones, Shu Li, Gavin P. Andrews, Construction of Drug–Polymer Thermodynamic Phase Diagrams Using Flory–Huggins Interaction Theory: Identifying the Relevance of Temperature and Drug Weight Fraction to Phase Separation within Solid Dispersions Molecular Pharmaceutics. ,vol. 10, pp. 236- 248 ,(2013) , 10.1021/MP300386V
Fusao Usui, Kazuko Maeda, Akira Kusai, Kenji Nishimura, Keiji Yamamoto, Inhibitory effects of water-soluble polymers on precipitation of RS-8359 International Journal of Pharmaceutics. ,vol. 154, pp. 59- 66 ,(1997) , 10.1016/S0378-5173(97)00129-4
Jiannan Lu, Sejal Shah, Seongbong Jo, Soumyajit Majumdar, Andreas Gryczke, Karl Kolter, Nigel Langley, Michael A. Repka, Investigation of phase diagrams and physical stability of drug–polymer solid dispersions Pharmaceutical Development and Technology. ,vol. 20, pp. 105- 117 ,(2015) , 10.3109/10837450.2014.949269