Protective effect of a new amide compound from Pu-erh tea on human micro-vascular endothelial cell against cytotoxicity induced by hydrogen peroxide

作者: Liang Zhang , Zhi-Zhong Ma , Yan-Yun Che , Ning Li , Peng-Fei Tu

DOI: 10.1016/J.FITOTE.2010.10.009

关键词:

摘要: Abstract A new amide, N-(3,4-dihydroxybenzoyl)-3,4-dihydroxybenzamide (1), was isolated from the Pu-erh tea made with leaf of Camellia assamica (Mast.) Chang by special fermentation techniques bacteria and fungus. Its structure established means spectroscopic data analyses, including mass spectrometry both 1D 2D NMR spectroscopy. Human micro-vascular endothelial cell (HMEC) injured H2O2 used as model to test protective effect compound 1 in contrast other known compounds tea. These results suggested that is a very useful prevent H2O2-induced death HMEC.

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