Use of different transmission metrics to describe malaria epidemiology in the highlands of western Kenya

摘要: Monitoring and evaluation of malaria programmes may require a combination approaches to detect any effects control. This is particularly true at lower transmission levels where detecting both infection exposure will provide additional evidence change. paper describes use three metrics explore the epidemiology in highlands western Kenya. A malariometric survey was conducted June 2009 two highland districts, Kisii Rachuonyo South, Nyanza Province, Kenya using cluster design. Enumeration areas were used sample 46 clusters from which 12 compounds randomly sampled. Individuals provided finger-blood assess (rapid diagnostic test, PCR) (anti-Plasmodium falciparum MSP-1 antibodies) questionnaire administered record household factors vector control interventions. Malaria prevalence rates 3.0 % (95 % CI 2.2–4.2 %) by rapid test (RDT) 8.5 % 7.0–10.4 %) PCR these ranged 0–13.1 0–14.8 % between for RDT PCR, respectively. Seroprevalence 36.8 % 33.9–39.8) ranging 18.6 65.8 %. Both prevalences highest children aged 5–10 years but proportion infections that sub-patent those 15 20 years age (78.1 %, 95 % 63.0–93.3 %) greater than (73.3 %, 64.5–81.9 %). Those reporting indoor residual spraying (IRS) their home bed nets had compared who reported IRS or alone. In this site low, highly heterogeneous. To accurately characterize extent transmission, more sensitive complementary such as serology are required addition standard microscopy and/or RDTs routinely used. likely be case other low endemicity settings.