Reversibility of brain tissue loss in anorexia nervosa assessed with a computerized Talairach 3-D proportional grid.

摘要: We describe the results of our follow-up magnetic resonance imaging (MRI) study underweight patients with anorexia nervosa, using rigorous methodology to control for head position across time. All subjects first underwent an initial scan and rescan verify that computerized three-dimensional co-planar grid method volume measurement was reliable accurate, regardless positioning. After a period several months, had assess changes may have occurred following significant weight gain. Ventricular total brain measurements from scans were compared age- sex-matched normal group determine whether we could replicate previous findings ventricular enlargement controls is reduced controls. Anorexic significantly larger ventricles when but did not differ in volume. Using repeated measures analysis variance, priori contrasts initial/rescan pair volumes each other These analyses showed derived nearly identical, at decreased increased after