The Role of Arterial Chemoreceptors in Ventilatory Acclimatization to Hypoxia

摘要: Mechanisms of ventilatory control responsible for increased breathing on ascent to altitude have been the object great interest respiratory physiologists many generations (cf. Kellogg, 1977). On exposure a hypoxic environment there is time dependent progressive rise in ventilation which commonly termed acclimatization hypoxia (VAH). This paper will explore findings associated with VAH, but not deal mechanisms very long-term residents or natives high altitude. Previously was strong focus central medullary chemoreceptors as source drive during evidence (to be briefly reviewed below) has failed support this view. Increasing accumulated suggesting that peripheral constitute primary site VAH. The research relevant role (carotid body) chapter. reader referred another recent review topic (Weil, 1991).