Tea Catechins Reduce Serum Cholesterol Levels in Mild and Borderline Hypercholesterolemia Patients

摘要: Blood cholesterol-lowering effect and safety of tea catechins were examined in a placebo-controlled double-blind study which beverage containing (a 250ml 197.4mg catechins) was given twice day at breakfast dinner for 12 weeks. The subjects used adult males females with mild borderline hypercholesterolemia the range serum total cholesterol levels 180-259mg/dl (male/ female, 38/22; age, 48±9 years; cholesterol, 222±20mg/dl), who not taking drugs that may affect lipid metabolism. initiated 2-week pre-observation period followed by 12-week intake post-observation period. results revealed test group (initial level) significantly decreased 8 weeks (228±23mg/dl to 220±21mg/dl, p<0.01) decrease maintained until (222±20mg/dl, p<0.05). Such significant decreases observed placebo any time points. In terms safety, no abnormal findings noted blood tests, physical measurements interviews physicians. Thus these demonstrated benefits individuals or hypercholesterolemia.