Clinical evaluation of contrast-enhanced digital mammography and contrast enhanced tomosynthesis—Comparison to contrast-enhanced breast MRI

摘要: Abstract Purpose To compare the diagnostic accuracy of contrast-enhanced digital mammography (CEDM) and tomosynthesis (CET) to dynamic contrast enhanced breast MRI (DCE-MRI) using a multireader-multicase study. Methods Institutional review board approval informed consents were obtained. Total 185 patients (mean age 51.3) with BI-RADS 4 or 5 lesions evaluated before biopsy mammography, tomosynthesis, CEDM, CET DCE-MRI. Mediolateral-oblique cranio-caudal views target CEDM acquired at 2 4 min after agent injection. A mediolateral-oblique view non-target was taken 6 min. Each lesion scored forced categories by three readers. reader interpreted in following order: CET, DCE-MRI during single reading session. Results Histology showed 81 cancers 144 benign Of malignant lesions, 44% (36/81) invasive 56% (45/81) non-invasive. Areas under ROC curve, averaged for 3 readers, as follows: 0.897 DCE-MRI, 0.892 0.878 0.784 0.740 mammography. Significant differences AUC found between group modalities (CEDM, DCE-MRI) unenhanced (all p   0.05). Conclusion may be considered an alternative modality up women abnormal All superior conventional without tomosynthesis.