Impact of endocrine toxicants on survival, development, and reproduction of the estuarine copepod Eurytemora affinis (Poppe)

摘要: Given recent reports suggesting that certain contaminants may be present in sewage effluents at levels, which exert a deleterious impact on fish, it seems pertinent to extend ecological hazard evaluation for such substances aquatic invertebrates. For this reason, we sought determine whether 17beta-estradiol (E2), benzo(a)pyrene (BaP), 4-nonylphenol (NP), di(ethyl-hexyl)-phthalate (DEHP), and atrazine (A), individually or binary mixture, can inhibit the survival, development, reproductive output of estuarine copepod Eurytemora affinis. In first experiment nauplii were exposed graded concentrations individual 96-h LC50, 10-day no observed effect concentration (NOEC) lowest each compound. second newly released (<24-h-old) either an contaminant NOEC mixtures, where compound was used half NOEC. The effects monitored daily development sex ratio. After 10 days exposure, adult males females paired exposures continued investigate (maximum 28 day total exposure). Based these life cycle parameters NOECs 6+/-4 microg L(-1) E2, 7+/-3 NP, 12+/-3 BaP, 25+/-3 A, 109+/-29 DEHP. DEHP inhibited naupliar but mixture with E2 compounds did not larval development. results suggest endocrine disruption could occur copepods following exposure estrogenic compounds, especially if they are starting from embryonic