Lipid A in Cancer Therapies Preclinical Results
作者： Daniele Reisser , Jean-François Jeannin
DOI: 10.1007/978-1-4419-1603-7_9
关键词:
摘要: Studies in animal models showed that the antitumoral effect of LPS and their biologically active moiety, lipid A, is indirect relies on induction an immune response both innate specific, leading to cytokine production. They also affect tumor development by inhibiting blood flow induce necrosis as well apoptosis cells. Lipids A have been tested animals, either alone or adjuvant therapeutic vaccines. The efficacy treatments depends type molecule protocol. In general, increased survival was obtained, accompanied some cases regression cure.
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