New-onset epilepsy in the elderly.

摘要: People who are 60 years old and older have the highest incidence of developing new-onset epilepsy. The increase ageing population has resulted in a greater number patients with epilepsy or at risk condition. Previously published review articles regarding had broad focus, including people were diagnosed their childhood middle age. present focuses on causes, treatment, prognosis psychosocial impact aged ≥60 years. Following search medical electronic databases relevant references, we identified 22 studies overall that met inclusion criteria. Only four randomized clinical trials (RCTs) compared different antiepileptic drug treatments this population, demonstrating newer-generation drugs (e.g. lamotrigine levetiracetam) generally better tolerated. One uncontrolled study provided promising evidence good outcomes safety for surgical resection as treatment seizures. Five reported significant cognitive impairments memory loss) psychological issues depression, anxiety fatigue. We found there is limited to guide Alzheimer's disease specific features target significantly influences choice treatment. Cognitive psychiatric screening before may be useful management. Two proposed guidelines but no formal practice exist special assist appropriate There need more RCTs investigate effective side effects. More research effects epilepsy, long-term outcomes, also required.