IMIDAZO[1,2-a](PYRROLO, THIENO OR FURANO)[3,2-d]AZEPINE DERIVATIVES, COMPOSITIONS AND METHODS OF USE

摘要: The present invention is concerned with novel imidazo[1,2-a](pyrrolo, thieno or furano)[3,2-d]azepines of formula (I), the pharmaceutically acceptable addition salts and stereochemically isomeric forms thereof, wherein each dotted lines independently represents an optional bond; R1 hydrogen, C?1-4?alkyl, halo, ethenyl substituted hydroxycarbonyl C1-4alkyloxycarbonyl, hydroxyC1-4alkyl, formyl, hydroxycarbonylC1-4alkyl; R?2? C1-4alkyl formyl hydroxycarbonyl; R?3? phenyl halo; L hydrogen; C1-6alkyl; C1-6alkyl one substituent selected from group consisting hydroxy, C1-4alkyloxy, hydroxycarbonyl, C1-4alkyloxycarbonylC1-4alkyloxy, hydroxycarbonylC1-4alkyloxy, C1-4alkyloxycarbonylamino, C1-4alkylaminocarbonyl, C1-4alkylaminocarbonylamino, C1-4alkylaminothiocarbonylamino, aryl, aryloxy arylcarbonyl; both hydroxy aryloxy; C3-6alkenyl; C3-6alkenyl aryl; a radical -Alk-Y-Het?1? (a-1), -Alk-NH-CO-Het2 (a-2) -Alk-Het3 (a-3); which are useful antiallergic compounds. Compositions comprising said compounds, methods using, processes for preparing same.