Thyroid Hormone Excess Rather Than Thyrotropin Deficiency Induces Osteoporosis in Hyperthyroidism
作者： J. H. Duncan Bassett , Patrick J. O’Shea , Srividya Sriskantharajah , Bénédicte Rabier , Alan Boyde
DOI: 10.1210/ME.2007-0033
关键词:
摘要: … thyroid hormone receptor α or β (TRα 0/0 , TRβ −/− ). Remarkably, in the presence of normal circulating thyroid hormone … bone resorption, whereas juveniles had delayed endochondral …
oup.com
elsevier.com
endocrine.org
endojournals.org
researchgate.net 参考文章(51)
D. Forrest, E. Hanebuth, R. J. Smeyne, N. Everds, C. L. Stewart, J. M. Wehner, T. Curran, Recessive resistance to thyroid hormone in mice lacking thyroid hormone receptor beta: evidence for tissue-specific modulation of receptor function. The EMBO Journal. ,vol. 15, pp. 3006- 3015 ,(1996) , 10.1002/J.1460-2075.1996.TB00664.X
R. C. Marians, L. Ng, H. C. Blair, P. Unger, P. N. Graves, T. F. Davies, Defining thyrotropin-dependent and -independent steps of thyroid hormone synthesis by using thyrotropin receptor-null mice. Proceedings of the National Academy of Sciences of the United States of America. ,vol. 99, pp. 15776- 15781 ,(2002) , 10.1073/PNAS.242322099
M C Sheppard, S R Jones, K W Cross, J A Franklyn, J V Parle, Thyroxine prescription in the community: serum thyroid stimulating hormone level assays as an indicator of undertreatment or overtreatment. British Journal of General Practice. ,vol. 43, pp. 107- 109 ,(1993)
David A. Stevens, Clare B. Harvey, Anthea J. Scott, Patrick J. O’Shea, Joanna C. Barnard, Allan J. Williams, Gerard Brady, Jacques Samarut, Olivier Chassande, Graham R. Williams, Thyroid hormone activates fibroblast growth factor receptor-1 in bone. Molecular Endocrinology. ,vol. 17, pp. 1751- 1766 ,(2003) , 10.1210/ME.2003-0137
P. Vestergaard, L. Rejnmark, L. Mosekilde, Influence of Hyper- and Hypothyroidism, and the Effects of Treatment with Antithyroid Drugs and Levothyroxine on Fracture Risk Calcified Tissue International. ,vol. 77, pp. 139- 144 ,(2005) , 10.1007/S00223-005-0068-X
E.F. Eriksen, L. Mosekilde, F. Melsen, Kinetics of trabecular bone resorption and formation in hypothyroidism: Evidence for a positive balance per remodeling cycle Bone. ,vol. 7, pp. 101- 108 ,(1986) , 10.1016/8756-3282(86)90681-2
Sönke Friedrichsen, Stephanie Christ, Heike Heuer, Martin K. H. Schäfer, Ahmed Mansouri, Karl Bauer, Theo J. Visser, Regulation of iodothyronine deiodinases in the Pax8(-/-) mouse model of congenital hypothyroidism Endocrinology. ,vol. 144, pp. 777- 784 ,(2003) , 10.1210/EN.2002-220715
Nancy Fox Ray, Julien K. Chan, Mae Thamer, L. Joseph Melton, Medical Expenditures for the Treatment of Osteoporotic Fractures in the United States in 1995: Report from the National Osteoporosis Foundation Journal of Bone and Mineral Research. ,vol. 12, pp. 24- 35 ,(1997) , 10.1359/JBMR.1997.12.1.24
Douglas C. Bauer, Bruce Ettinger, Michael C. Nevitt, Katie L. Stone, , Risk for Fracture in Women with Low Serum Levels of Thyroid-Stimulating Hormone Annals of Internal Medicine. ,vol. 134, pp. 561- 568 ,(2001) , 10.7326/0003-4819-134-7-200104030-00009
Karine Gauthier, Olivier Chassande, Michela Plateroti, Jean‐Paul Roux, Claude Legrand, Bertrand Pain, Bernard Rousset, Roy Weiss, Jacqueline Trouillas, Jacques Samarut, Different functions for the thyroid hormone receptors TRα and TRβ in the control of thyroid hormone production and post‐natal development The EMBO Journal. ,vol. 18, pp. 623- 631 ,(1999) , 10.1093/EMBOJ/18.3.623