Tailored chemotherapy based on tumour gene expression analysis: breast cancer patients' misinterpretations and positive attitudes

摘要: PELLEGRINI I., RAPTI M., EXTRA J.-M., PETRI-CAL A., APOSTOLIDIS T., FERRERO BACHELOT VIENS P., JULIAN-REYNIER C. & BERTUCCI F. (2011) European Journal of Cancer Care21, 242–250 Tailored chemotherapy based on tumour gene expression analysis: breast cancer patients' misinterpretations and positive attitudes The aim this study was to document how patients perceive their prognosis a tailored treatment analysis, identify the features approach that may impact its clinical application. In-depth interviews were conducted at three French centres with 37 women (35–69 years age) node-positive undergoing an adjuvant regimen defined basis genomic signature predicting outcome after chemotherapy. Several concerns identified. First, some misconceptions about these methods identified due semantic confusions between terms ‘genomic’ ‘genetic’, which generated anxiety uncertainty future. Second, ‘not done’ interpretable’ signatures misinterpreted by associated highly negative connotations. However, use analysis adapt each patient received most approval because it perceived as facilitating personalised medicine. In conclusion, improving quality provider/patient communications should enable play more active part in decision making treatment. This will ensure those who agree have realistic expectations sound deductions final result disclosure process.