An algorithm to analyze stability of gene-expression patterns

作者: J. Gebert , M. Lätsch , S.W. Pickl , G.-W. Weber , R. Wünschiers

DOI: 10.1016/J.DAM.2004.08.011

关键词:

摘要: Many problems in the field of computational biology consist analysis so-called gene-expression data. The successful application approximation and optimization techniques, dynamical systems, algorithms utilization underlying combinatorial structures lead to a better understanding that field. For concrete example data we extend an algorithm, which exploits discrete information. This is lying extremal points polyhedra, grow step by step, up possible stopping. We study time, mathematically model it time-continuous system, time-discretize this system. By our algorithm compute regions stability instability. give motivating introduction from genetics, present biological mathematical interpretations (in)stability, point out structural frontiers outlook future research.

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