Linking emerging contaminants exposure to adverse health effects: Crosstalk between epigenome and environment

摘要: Environmental epigenetic findings shed new light on the roles of regulations in environmental exposure-induced toxicities or disease susceptibilities. Currently, emerging contaminants (ECs) are focus for further investigation due to evidence human exposure addition their occurrences. However, adverse effects these ECs health through mechanisms still poorly addressed many aspects. This review discusses (DNA methylation, histone modifications, and microRNA expressions) linking outcomes. We emphasized recent literature describing how can dysregulate lead downstream These up-to-date research outputs could provide novel insights into toxicological ECs. field faces a demand studies broad spectrum effects, synergistic/antagonistic transgenerational epidemiologic demographic data