Mechanical Properties and Microstructure of Intraluminal Thrombus From Abdominal Aortic Aneurysm

摘要: Accurate estimation of the wall stress distribution in an abdominal aortic aneurysm (AAA) may prove clinically useful by predicting when a particular will rupture. Appropriate constitutive models for both and intraluminal thrombus (ILT) found most AAA are necessary this task. The purpose work was to determine mechanical properties ILT within derive more suitable model material. Uniaxial tensile testing carried out on 50 specimens, including 14 longitudinally oriented circumferentially specimens from luminal region ILT, 11 medial region. A two-parameter, large-strain, hyperelastic developed used fit uniaxial data determination material parameters. Maximum stiffness strength were also determined each specimen, Scanning electron microscopy (SEM) conducted study regional microstructural difference. Our results indicate that microstructure differs between luminal, medial, abluminal regions, with stronger stiffer than In all cases, experimental very well (R 2 >0.98). No significant difference either two parameters longitudinal circumferential directions, but parameters, stiffness, regions (p<0.01). Therefore, our suggest is inhomogeneous possibly isotropic hyperelastic, isotropic, incompressible derived here can be easily incorporated into finite element simulation AAA.