Phase-Contrast Diffuse Optical Tomography
作者： Xiaoping Liang , Qizhi Zhang , Changqing Li , Stephen R. Grobmyer , Laurie L. Fajardo
DOI: 10.1016/J.ACRA.2008.01.028
关键词:
摘要: Rationale and Objectives We sought to investigate the utility of phase-contrast diffuse optical tomography (PCDOT) for differentiation malignant benign breast masses in humans compare PCDOT with conventional (DOT) analysis humans. Materials Methods Thirty-five were imaged 33 patients (mean age, 51 years; range, 22–80) using PCDOT. Images characterizing tissue refractive index, absorption scattering coefficients obtained a finite element-based reconstruction algorithm. Theses images then analyzed compared biopsy/pathology results all cases examined. Results Malignant lesions tended have decreased allowing them be discriminated from most cases, whereas unable accurately discriminate lesions. The sensitivity, specificity, false-positive value, overall accuracy index imaging 81.8%, 70.8%, 29.2%, 74.3%, respectively. increases increasing patient age. Conclusion Refractive is new parameter that may helpful differentiating between breast.
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