Haplotype analysis of the 5,10-methylenetetrahydrofolate reductase (MTHFR) c.1298A>C (E429A) polymorphism
作者： Alexander Semmler , Susanna Moskau , Holger Lutz , Peter Meyer , Michael Linnebank
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摘要: Background The polymorphism 5,10-methylenetetrahydrofolate reductase (MTHFR) c.1298A>C is associated with various diseases. 45 DNA samples homozygous for the A allele and 40 probes C were taken from healthy German subjects of white Caucasian origin to analyze haplotype two MTHFR alleles. Samples genotyped c.677C>T silent polymorphisms c.129C>T, IVS2 533 G>A, c.1068C>T IVS10 262C>G.
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